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Marburg virus

Marburg virus

Recently, West Africa’s first instance of the incredibly infectious and destructive Marburg infection was affirmed in Guinea. Its first case was first recognized only two months after the nation was announced liberated from Ebola. Both the Marburg case and the current year’s Ebola cases were identified in Guinea’s Gueckedou region. The main instances of the 2014-2016 Ebola plague, the biggest ever, likewise were from a similar district in Southeastern Guinea’s backwoods locale.

Marburg infection sickness is a profoundly destructive illness that causes hemorrhagic fever, it is conveyed by bats with a casualty proportion of up to 88%. It is in the very family as the infection that causes Ebola infection sickness.

Two huge flare-ups that happened at the same time in Marburg and Frankfurt in Germany, and in Belgrade, Serbia, in 1967, prompted the underlying acknowledgment of the infection. The flare-up was related to research center work utilizing African green monkeys (Cercopithecus aethiops) imported from Uganda.

Consequently, flare-ups and inconsistent cases have been accounted for in Angola, the Democratic Republic of the Congo, Kenya, South Africa, and Uganda. There have been 12 significant Marburg flare-ups since 1967, for the most part in southern and eastern Africa.

Human infection with Marburg virus disease initially results from prolonged exposure to mines or caves inhabited by Rousettus bat colonies. Rousettus is a genus of Old World fruit bats or megabats.

Once an individual is infected with the virus, Marburg can spread through human-to-human transmission via direct contact.

Its symptoms are headache, vomiting blood, muscle pains, and bleeding through various orifices. Symptoms become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, liver failure, massive hemorrhaging, and multi-organ dysfunction.

There is no specific treatment or approved vaccine for Marburg hemorrhagic fever. Supportive hospital therapy should be utilized.
Supportive hospital therapy includes balancing the patient’s fluids and electrolytes, maintaining oxygen status and blood pressure, replacing lost blood and clotting factors, and treatment for any complicating infections.

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Nikhil Thakur

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